HuagongsheHuagongshe Chemistry Print Report · For research reference only
n-(4-Tert-butylphenyl)-2-fluoronicotinamide → N-(4-tert-Butylphenyl)-2-[(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | n-(4-Tert-butylphenyl)-2-fluoronicotinamide | HCID 21959540 | — |
| Reactant | C-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-yl)-methylamine dihydrochloride | HCID 69263942 | — |
| Product | N-(4-tert-Butylphenyl)-2-[(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide | HCID 16224615 | — |
Reaction Steps
The titled compound was prepared from N-(4-tert-butyl-phenyl)-2-fluoro-nicotinamide and C-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-yl)-methylamine dihydrochloride by the method described in Step A of Example 1. MS (ES+): 402 (M+H). Calc'd. for C24H27N5O—401.51.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247556B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-1bde5c2dc4454a0f83d4bd870fa97b20 |
| Source note | uspto-grants-2012_08 |