2-Methylpiperazine, (S)- → HCID 58488043, compound

HRID 888173Notes

Reaction equation

HRID 888173 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][NH:11][C@H:10]([CH3:14])[CH2:9]1.C[C@H]1CNCCN1>C(Cl)(Cl)Cl.CO>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][NH:11][C@@H:10]([CH3:14])[CH2:9]1

Participants

4

Reactant 2

HCID 27342192-Methylpiperazine, (S)-HCID 11600842HCID 11600842, compound

Product 1

HCID 58488043HCID 58488043, compound

Reagents, catalysts & solvents 1

HCID 21584188Chloroform methanolSolvent

Procedure

The title compound was prepared following the protocol used for the preparation of Intermediate 5, but starting from (S)-2-methylpiperazine (40%). TLC-Chloroform/Methanol (9/1); Rf: 0.25. HPLC purity: 97%.

Sources & evidence

ORD record
ord-4b37098db21343279d6e60ae82b65d1b
Source dataset
uspto-grants-2012_08
Patent number
US08247437B2

Reaction notes

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