Pivaloyl chloride → HCID 58372773, compound

HRID 888475Notes

Reaction equation

[CH2:1]([O:3][C:4](=[O:28])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([NH2:21])=[CH:17][C:16]=2[CH2:22][S:23][C:24]([CH3:27])([CH3:26])[CH3:25])[CH:7]=1)[CH3:2].[C:29](Cl)(=[O:34])[C:30]([CH3:33])([CH3:32])[CH3:31]>>[CH2:1]([O:3][C:4](=[O:28])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([NH:21][C:29](=[O:34])[C:30]([CH3:33])([CH3:32])[CH3:31])=[CH:17][C:16]=2[CH2:22][S:23][C:24]([CH3:27])([CH3:26])[CH3:25])[CH:7]=1)[CH3:2]

Participants

Reactant 2

HCID 62493Pivaloyl chloride

HCID 58372767HCID 58372767, compound

Product 1

HCID 58372773HCID 58372773, compound

Procedure

Prepared according to the procedure described in Example 3, Step 6, using the following starting materials: [3-(4-amino-2-tert-butylsulfanylmethyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester and pivaloyl chloride.

Workup

customPrepared

Sources & evidence

ORD record: ord-65f31efa9980490c818cdfd6d3cfa36e
Source dataset: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08247602B2

Reaction notes

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