2,2,2-Trifluoroethyl Methanesulfonate → 4-Iodo-2-methyl-1-(2,2,2-trifluoroethyl)-1H-imidazole

HRID 8885Notes

Reaction equation

HRID 8885 reaction equation
[I:1][C:2]1[NH:6][C:5]([CH3:7])=[N:4][CH:3]=1.S(O[CH2:13][C:14]([F:17])([F:16])[F:15])(=O)(=O)C>>[I:1][C:2]1[N:6]=[C:5]([CH3:7])[N:4]([CH2:13][C:14]([F:17])([F:16])[F:15])[CH:3]=1

Participants

3

Reactant 2

HCID 5565652,2,2-Trifluoroethyl MethanesulfonateHCID 27946235-Iodo-2-methyl-1H-imidazole

Product 1

HCID 219853984-Iodo-2-methyl-1-(2,2,2-trifluoroethyl)-1H-imidazole

Procedure

The title compound, MS: m/e=291.0 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-methyl-1H-imidazole and 2,2,2-trifluoroethyl mesylate.

Sources & evidence

ORD record
ord-78744fdb607348e4bd18f3e963ba1543
Source dataset
uspto-grants-2006_08
Patent number
US07091222B2

Reaction notes

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