2-Chloroethyl chloroformate → HCID 58372793, compound

HRID 888513Notes

Reaction equation

HRID 888513 reaction equation
[CH2:1]([O:3][C:4](=[O:29])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([NH2:21])=[CH:17][C:16]=2[CH2:22][S:23][CH2:24][C:25]([F:28])([F:27])[F:26])[CH:7]=1)[CH3:2].Cl[C:31]([O:33][CH2:34][CH2:35][Cl:36])=[O:32]>>[CH2:1]([O:3][C:4](=[O:29])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([NH:21][C:31]([O:33][CH2:34][CH2:35][Cl:36])=[O:32])=[CH:17][C:16]=2[CH2:22][S:23][CH2:24][C:25]([F:26])([F:27])[F:28])[CH:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 123052-Chloroethyl chloroformateHCID 58372871HCID 58372871, compound

Product 1

HCID 58372793HCID 58372793, compound

Procedure

Prepared according to the procedure described in Example 3, Step 6, using the following starting materials: {3-[4-amino-2-(2,2,2-trifluoro-ethylsulfanylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl ester and 2-chloroethyl chloroformate.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a911acdfbfb9445795d0c40df756bdfd
Source dataset
uspto-grants-2012_08
Patent number
US08247602B2

Reaction notes

Loading…