2-Fluoro-5-nitrobenzaldehyde → HCID 58372875, compound

HRID 888527Notes

Reaction equation

HRID 888527 reaction equation
[CH2:1]([O:3][C:4](=[O:14])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]([OH:13])[CH:7]=1)[CH3:2].F[C:16]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][C:17]=1[CH:18]=[O:19]>>[CH2:1]([O:3][C:4](=[O:14])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]([O:13][C:16]2[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][C:17]=2[CH:18]=[O:19])[CH:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 27347702-Fluoro-5-nitrobenzaldehydeHCID 58785142HCID 58785142, compound

Product 1

HCID 58372875HCID 58372875, compound

Procedure

(4-Chloro-3-hydroxy-phenyl)-acetic acid ethyl ester was reacted with 2-fluoro-5-nitrobenzaldehyde as outlined in Example 21, Step 5, to provide [4-chloro-3-(2-formyl-4-nitro-phenoxy)-phenyl]-acetic acid ethyl ester.

Sources & evidence

ORD record
ord-191c9910a17e4385b9f1d7eca4509ab0
Source dataset
uspto-grants-2012_08
Patent number
US08247602B2

Reaction notes

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