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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 888586Generated: October 25, 2026

4-Chloro-beta-(4-chlorophenyl)benzeneethanol → 2-(4-Chloro-phenyl)-2-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol

https://huagongshe.com/reaction/888586

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-beta-(4-chlorophenyl)benzeneethanolHCID 17533—
Reactant4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 2774010—
Product2-(4-Chloro-phenyl)-2-[4-(1H-pyrazol-4-yl)-phenyl]-ethanolHCID 59331931—

Reaction Steps

2,2-Bis-(4-chloro-phenyl)-ethanol was reacted with 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole following the procedure set out in Example 1 to give the title compound. LC/MS: (PS-A2) Rt 2.72 [M+]+ 299.00.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08247576B2
Source datasetuspto-grants-2012_08
ORD IDord-0f49ed58e09d48eb89b20f325db6307c
Source noteuspto-grants-2012_08