3-Fluoro-5-(trifluoromethyl)benzeneboronic acid → 2-(3'-Fluoro-5-trifluoromethanesulfonyloxy-5'-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester

Participants

Reaction Steps

The title compound was prepared in 66% yield from 2-(3-benzyloxy-5-trifluoromethanesulfonyloxy-phenyl)-4-methyl-pent-4-enoic acid methyl ester (prepared in Example 1, step (d)) under the conditions described in Example 1, step (e-g)) using 3-fluoro-5-trifluoromethylphenylboronic acid in step (e).

Provenance & Evidence