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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 888770Generated: October 31, 2026

1-(Bromomethyl)-4-chlorobenzene → 1-(4-Chlorobenzyl)-4,4-dimethyl-2-(adamantan-2-yl)-1,2-diazetidin-3-one

https://huagongshe.com/reaction/888770

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-4-chlorobenzeneHCID 69329—
Reactant2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-oneHCID 67302882—
Product1-(4-Chlorobenzyl)-4,4-dimethyl-2-(adamantan-2-yl)-1,2-diazetidin-3-oneHCID 46194785—

Reaction Steps

2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one prepared in Process 3 of Example 12, and 4-chlorobenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a white crystalline powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08252781B2
Source datasetuspto-grants-2012_08
ORD IDord-685672999eb14bd784c93b51df7a4e00
Source noteuspto-grants-2012_08