p-Xylyl bromide → HCID 46194926, compound

HRID 888771Notes

Reaction equation

HRID 888771 reaction equation
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[N:11]1[C:14](=[O:15])[C:13]([CH3:17])([CH3:16])[NH:12]1)[CH2:8]2.[CH3:18][C:19]1[CH:26]=[CH:25][C:22]([CH2:23]Br)=[CH:21][CH:20]=1>>[CH3:16][C:13]1([CH3:17])[N:12]([CH2:18][C:19]2[CH:26]=[CH:25][C:22]([CH3:23])=[CH:21][CH:20]=2)[N:11]([CH:2]2[CH:3]3[CH2:4][CH:5]4[CH2:6][CH:7]([CH2:8][CH:1]2[CH2:10]4)[CH2:9]3)[C:14]1=[O:15]

Participants

3

Reactant 2

HCID 7721p-Xylyl bromideHCID 673028822-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one

Product 1

HCID 46194926HCID 46194926, compound

Procedure

2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one and 4-methylbenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a white crystalline powder.

Sources & evidence

ORD record
ord-94d456fabba243d3bafac19d6a6f3885
Source dataset
uspto-grants-2012_08
Patent number
US08252781B2

Reaction notes

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