HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Bromomethyl)-3-fluoro-5-(trifluoromethyl)benzene → 1-[3-Fluoro-5-(trifluoromethyl)benzyl]-4,4-dimethyl-2-(adamantan-2-yl)-1,2-diazetidin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Bromomethyl)-3-fluoro-5-(trifluoromethyl)benzene | HCID 2737575 | — |
| Reactant | 2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one | HCID 67302882 | — |
| Product | 1-[3-Fluoro-5-(trifluoromethyl)benzyl]-4,4-dimethyl-2-(adamantan-2-yl)-1,2-diazetidin-3-one | HCID 46195066 | — |
Reaction Steps
2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one and 3-fluoro-5-(trifluoromethyl)benzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08252781B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-2195ccffe72441b4b444924e4dfc56f4 |
| Source note | uspto-grants-2012_08 |