1-(Bromomethyl)-3-chlorobenzene → HCID 59361411, compound

HRID 888785Notes

Reaction equation

HRID 888785 reaction equation
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[N:11]1[C:14](=[O:15])[C:13]([CH3:17])([CH3:16])[NH:12]1)[CH2:8]2.[Cl:18][C:19]1[CH:20]=[C:21]([CH:24]=[CH:25][CH:26]=1)[CH2:22]Br>>[Cl:18][C:19]1[CH:20]=[C:21]([CH:24]=[CH:25][CH:26]=1)[CH2:22][N:12]1[C:13]([CH3:17])([CH3:16])[C:14](=[O:15])[N:11]1[CH:2]1[CH:3]2[CH2:4][CH:5]3[CH2:6][CH:7]([CH2:8][CH:1]1[CH2:10]3)[CH2:9]2

Participants

3

Procedure

2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one and 3-chlorobenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a white crystalline powder.

Sources & evidence

ORD record
ord-bcae633c16df40a093926a149264da98
Source dataset
uspto-grants-2012_08
Patent number
US08252781B2

Reaction notes

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