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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 888805Generated: October 27, 2026

4-Fluoro-2-(trifluoromethyl)benzyl bromide → 1-[4-Fluoro-2-(trifluoromethyl)benzyl]-4,4-dimethyl-2-(adamantan-2-yl)-1,2-diazetidin-3-one

https://huagongshe.com/reaction/888805

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-(trifluoromethyl)benzyl bromideHCID 2737576—
Reactant2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-oneHCID 67302882—
Product1-[4-Fluoro-2-(trifluoromethyl)benzyl]-4,4-dimethyl-2-(adamantan-2-yl)-1,2-diazetidin-3-oneHCID 46195359—

Reaction Steps

2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one and 4-fluoro-2-(trifluoromethyl)benzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08252781B2
Source datasetuspto-grants-2012_08
ORD IDord-36788400be3946dbb767a18d0e320514
Source noteuspto-grants-2012_08