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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 888813Generated: October 30, 2026

2-(Bromomethyl)-1,4-dimethylbenzene → 1-(2,5-Dimethylbenzyl)-4,4-dimethyl-2-(adamantan-2-yl)-1,2-diazetidin-3-one

https://huagongshe.com/reaction/888813

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)-1,4-dimethylbenzeneHCID 15166401—
Reactant2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-oneHCID 67302882—
Product1-(2,5-Dimethylbenzyl)-4,4-dimethyl-2-(adamantan-2-yl)-1,2-diazetidin-3-oneHCID 46195509—

Reaction Steps

2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one and 2,5-dimethylbenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a white crystalline powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08252781B2
Source datasetuspto-grants-2012_08
ORD IDord-f41540096958414298b2b577e112555f
Source noteuspto-grants-2012_08