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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 888819Generated: November 2, 2026

1,3-Benzodioxole, 5-(bromomethyl)- → 1-(1,3-Benzodioxol-5-ylmethyl)-4,4-dimethyl-2-(adamantan-2-yl)-1,2-diazetidin-3-one

https://huagongshe.com/reaction/888819

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Benzodioxole, 5-(bromomethyl)-HCID 6451423—
Reactant2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-oneHCID 67302882—
Product1-(1,3-Benzodioxol-5-ylmethyl)-4,4-dimethyl-2-(adamantan-2-yl)-1,2-diazetidin-3-oneHCID 46195640—

Reaction Steps

2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one and 3,4-(methylenedioxy)benzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a brown oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08252781B2
Source datasetuspto-grants-2012_08
ORD IDord-eb9068588f6246d793b928e7c1a860c4
Source noteuspto-grants-2012_08