alpha-Bromo-o-chlorotoluene → 1-(2-Chlorobenzyl)-2-cyclohexyl-4,4-dimethyl-1,2-diazetidin-3-one

HRID 888823Notes

Reaction equation

HRID 888823 reaction equation
[CH:1]1([N:7]2[C:10](=[O:11])[C:9]([CH3:13])([CH3:12])[NH:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:14][C:15]1[CH:22]=[CH:21][CH:20]=[CH:19][C:16]=1[CH2:17]Br>>[Cl:14][C:15]1[CH:22]=[CH:21][CH:20]=[CH:19][C:16]=1[CH2:17][N:8]1[C:9]([CH3:13])([CH3:12])[C:10](=[O:11])[N:7]1[CH:1]1[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 11905alpha-Bromo-o-chlorotolueneHCID 673030222-Cyclohexyl-4,4-dimethyl-1,2-diazetidin-3-one

Product 1

HCID 461956451-(2-Chlorobenzyl)-2-cyclohexyl-4,4-dimethyl-1,2-diazetidin-3-one

Procedure

2-Cyclohexyl-4,4-dimethyl-1,2-diazetidin-3-one and 2-chlorobenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a pale yellow oil.

Sources & evidence

ORD record
ord-51adf9347b24408a8ed59ed1148a07e7
Source dataset
uspto-grants-2012_08
Patent number
US08252781B2

Reaction notes

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