1-(Bromomethyl)-2,3-dichlorobenzene → 2-Cyclohexyl-1-(2,3-dichlorobenzyl)-4,4-dimethyl-1,2-diazetidin-3-one

HRID 888824Notes

Reaction equation

HRID 888824 reaction equation
[CH:1]1([N:7]2[C:10](=[O:11])[C:9]([CH3:13])([CH3:12])[NH:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:14][C:15]1[C:22]([Cl:23])=[CH:21][CH:20]=[CH:19][C:16]=1[CH2:17]Br>>[CH:1]1([N:7]2[C:10](=[O:11])[C:9]([CH3:13])([CH3:12])[N:8]2[CH2:17][C:16]2[CH:19]=[CH:20][CH:21]=[C:22]([Cl:23])[C:15]=2[Cl:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 27346021-(Bromomethyl)-2,3-dichlorobenzeneHCID 673030222-Cyclohexyl-4,4-dimethyl-1,2-diazetidin-3-one

Product 1

HCID 593614702-Cyclohexyl-1-(2,3-dichlorobenzyl)-4,4-dimethyl-1,2-diazetidin-3-one

Procedure

2-Cyclohexyl-4,4-dimethyl-1,2-diazetidin-3-one prepared in Process 5 of Example 68, and 2,3-dichlorobenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a pale yellow oil.

Workup

  1. customwere used for a similar reaction and treatment as Process 6 of Example 1

Sources & evidence

ORD record
ord-52166d6bbbbe47f89a9370872e1e5673
Source dataset
uspto-grants-2012_08
Patent number
US08252781B2

Reaction notes

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