1-(Bromomethyl)-2,3-dichlorobenzene → 2-Cyclooctyl-1-(2,3-dichlorobenzyl)-4,4-dimethyl-1,2-diazetidin-3-one

HRID 888830Notes

Reaction equation

HRID 888830 reaction equation
[CH:1]1([N:9]2[C:12](=[O:13])[C:11]([CH3:15])([CH3:14])[NH:10]2)[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:16][C:17]1[C:24]([Cl:25])=[CH:23][CH:22]=[CH:21][C:18]=1[CH2:19]Br>>[CH:1]1([N:9]2[C:12](=[O:13])[C:11]([CH3:15])([CH3:14])[N:10]2[CH2:19][C:18]2[CH:21]=[CH:22][CH:23]=[C:24]([Cl:25])[C:17]=2[Cl:16])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 27346021-(Bromomethyl)-2,3-dichlorobenzeneHCID 673029832-Cyclooctyl-4,4-dimethyl-1,2-diazetidin-3-one

Product 1

HCID 593614512-Cyclooctyl-1-(2,3-dichlorobenzyl)-4,4-dimethyl-1,2-diazetidin-3-one

Procedure

2-Cyclooctyl-4,4-dimethyl-1,2-diazetidin-3-one prepared in Process 5 of Example 73 and 2,3-dichlorobenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a colorless oil.

Workup

  1. customwere used for a similar reaction and treatment as Process 6 of Example 1

Sources & evidence

ORD record
ord-6843e4c8fedb44d1b32d4d52812e28ac
Source dataset
uspto-grants-2012_08
Patent number
US08252781B2

Reaction notes

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