1-(Bromomethyl)-2,3-dichlorobenzene → 2-(Bicyclo[2.2.1]heptan-2-yl)-1-(2,3-dichlorobenzyl)-4,4-dimethyl-1,2-diazetidin-3-one

HRID 888835Notes

Reaction equation

HRID 888835 reaction equation
[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[N:8]1[C:11](=[O:12])[C:10]([CH3:14])([CH3:13])[NH:9]1.[Cl:15][C:16]1[C:23]([Cl:24])=[CH:22][CH:21]=[CH:20][C:17]=1[CH2:18]Br>>[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[N:8]1[C:11](=[O:12])[C:10]([CH3:14])([CH3:13])[N:9]1[CH2:18][C:17]1[CH:20]=[CH:21][CH:22]=[C:23]([Cl:24])[C:16]=1[Cl:15]

Participants

3

Reactant 2

HCID 27346021-(Bromomethyl)-2,3-dichlorobenzeneHCID 673032332-(Bicyclo[2.2.1]heptan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one

Product 1

HCID 593614432-(Bicyclo[2.2.1]heptan-2-yl)-1-(2,3-dichlorobenzyl)-4,4-dimethyl-1,2-diazetidin-3-one

Procedure

2-(Bicyclo[2.2.1]heptan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one prepared in Process 5 of Example 78 and 2,3-dichlorobenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a colorless oil.

Workup

  1. customwere used for a similar reaction and treatment as Process 6 of Example 1

Sources & evidence

ORD record
ord-3c1cfd54a552459aac628b6aa4f4f0a2
Source dataset
uspto-grants-2012_08
Patent number
US08252781B2

Reaction notes

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