HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Bromomethyl)-2-chloro-4-fluorobenzene → 2-(Bicyclo[2.2.1]heptan-2-yl)-1-(2-chloro-4-fluorobenzyl)-4,4-dimethyl-1,2-diazetidin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Bromomethyl)-2-chloro-4-fluorobenzene | HCID 2725062 | — |
| Reactant | 2-(Bicyclo[2.2.1]heptan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one | HCID 67303233 | — |
| Product | 2-(Bicyclo[2.2.1]heptan-2-yl)-1-(2-chloro-4-fluorobenzyl)-4,4-dimethyl-1,2-diazetidin-3-one | HCID 46195784 | — |
Reaction Steps
2-(Bicyclo[2.2.1]heptan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one and 2-chloro-4-fluorobenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08252781B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-9adb613a317d4a29a4049c4c7686e653 |
| Source note | uspto-grants-2012_08 |