2-Chloro-5-fluorobenzyl bromide → HCID 59361416, compound

HRID 888838Notes

Reaction equation

HRID 888838 reaction equation
[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[N:8]1[C:11](=[O:12])[C:10]([CH3:14])([CH3:13])[NH:9]1.[Cl:15][C:16]1[CH:23]=[CH:22][C:21]([F:24])=[CH:20][C:17]=1[CH2:18]Br>>[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[N:8]1[C:11](=[O:12])[C:10]([CH3:14])([CH3:13])[N:9]1[CH2:18][C:17]1[CH:20]=[C:21]([F:24])[CH:22]=[CH:23][C:16]=1[Cl:15]

Participants

3

Reactant 2

HCID 27736232-Chloro-5-fluorobenzyl bromideHCID 673032332-(Bicyclo[2.2.1]heptan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one

Product 1

HCID 59361416HCID 59361416, compound

Procedure

2-(Bicyclo[2.2.1]heptan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one and 2-chloro-5-fluorobenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a colorless oil.

Sources & evidence

ORD record
ord-059a22d3a8da41d08e84d94d89ec38da
Source dataset
uspto-grants-2012_08
Patent number
US08252781B2

Reaction notes

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