HCID 59361436, compound → HCID 46194242, compound

Participants

Reaction Steps

A solution of 4,4-dimethyl-1-(4-nitrophenyl)-2-(adamantan-2-yl)-1,2-diazetidin-3-one (15.3 mg, 0.0430 mmol) prepared in Example 182 in ethanol (2 mL) was added with 10% palladium carbon (catalyst amount), and under a hydrogen atmosphere the resultant was stirred at room temperature for 20 minutes. The reaction solution was filtered using celite, concentrated in vacuo, the obtained residue was purified using Preparative Thin-Layer chromatography (hexane:ethyl acetate=1:1), and the title compound (14.2 m, quant.) was obtained as a colorless oil.

Provenance & Evidence