HCID 46194512, compound → HCID 59361487, compound

Participants

Reaction Steps

A solution of 4,4-dimethyl-1-[(E)-2-phenylethenyl]-2-(adamantan-2-yl)-1,2-diazetidin-3-one (38.4 mg, 0.103 mmol) prepared in Example 265 in methanol (2 mL) was added with 10% palladium carbon (catalyst amount), and the resultant was stirred at room temperature for 40 minutes under a hydrogen atmosphere. The reaction solution was filtered using celite, concentrated in vacuo, the obtained residue was purified using Preparatory Thin-Layer chromatography (hexane:ethyl acetate=2:1), and the title compound (1.80 mg, 5.20%) was obtained as a white crystalline powder.

Provenance & Evidence