HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 2-cyclopropyl-5-iodo-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Sodium Sulfite | HCID 24437 | — |
| Reactant | 2-cyclopropyl-1H-imidazole | HCID 17942383 | — |
| Reactant | 2-Cyclopropyl-4,5-diiodo-1h-imidazole | HCID 21985395 | — |
| Product | 2-cyclopropyl-5-iodo-1H-imidazole | HCID 21985392 | — |
Reaction Steps
The title compound was prepared in accordance with the literature reference of Cliff & Pyne, Synthesis-Stuttgart (7), 681–682(1994) by reacting 2-cyclopropyl-1H-imidazole with iodine in the presence of NaOH. The obtained 4,5-diiodo-2-cyclopropyl-1H-imidazole was then reacted with sodium sulfite to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091222B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-4a51539e54e6499c8098a02ac20b71d4 |
| Source note | uspto-grants-2006_08 |