Water → HCID 57927162, compound

Participants

Reaction Steps

After suspending 8-methyl-8H-imidazo[1,2-a][1,3,5]triazine-2,4-dione (CAS 67464-13-5) (100 mg) in N,N-dimethylformamide (2 ml), 1,3-dibromopropane (0.18 ml) and sodium hydride (60% in oil) (27 mg) were added and the mixture was stirred at room temperature for 14 hours. Water was added to the reaction mixture, and extraction was performed with ethyl acetate. The organic layer was washed with water and brine in that order and then dried over anhydrous magnesium sulfate. After filtration, the solvent was distilled off under reduced pressure. The obtained solid was washed with diethyl ether to obtain the title compound (68 mg).

Provenance & Evidence