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HRID889197

反应详情

EQUATION

反应方程式

HRID 889197 的结构方程式

REACTANTS

反应物

3
结构：CNC(=O)c1ccc(CCC(=O)O)cc1
HCID19603429

未命名化合物

结构：COc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CN)c3Cl)cccc2n1Cc1ccccn1
HCID66760385

未命名化合物

结构：COCCNC(=O)c1ccc(CCC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c3nc(OC)n4Cc3ccccn3)c2Cl)cc1
HCID66760978

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=O)c1ccc(CCC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c3nc(OC)n4Cc3ccccn3)c2Cl)cc1
HCID56839791

未命名化合物

PROCEDURE

实验过程

Compound 33 is prepared from 3-(4-(methylcarbamoyl)phenyl)propanoic acid and 2-amino-N-(2,4-dichloro-3-(((2-methoxy-1-(pyridin-2-ylmethyl)-1H-benzo[d]imidazol-4-yl)oxy)methyl)phenyl)-N-methylacetamide as described for compound 1. MS (ESI) 689 (M+) 1HNMR (CDCl3), 2.42-2.58 (m, 2H), 2.80-2.90 (m, 5H), 3.18 (s, 3H), 3.3-3.5 (m, 1H), 3.65-3.72 (m, 1H), 4.14 (s, 3H), 5.25 (s, 2H), 5.5-5.7 (m, 2H), 6.4-6.6 (m, 2H), 6.75-6.82 (m, 2H), 6.85-6.91 (m, 1H), 6.95-7.10 (m, 3H), 7.38-7.45 (m, 1H), 7.52-7.62 (m, 1H), 6.8-6.72 (m, 2H), 8.52-8.60 (m, 1H).