HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 3-(6-(Methylcarbamoyl)pyridin-3-yl)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 3-(2-Methylcarbamoyl-pyrimidin 5-yl)acrylic acid benzyl ester | HCID 66759306 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 3-(6-(Methylcarbamoyl)pyridin-3-yl)propanoic acid | HCID 66760221 | — |
Reaction Steps
3-(2-methylcarbamoyl-pyrimidin 5-yl)acrylic acid benzyl ester was dissolved in ethanol (20 mL) in presence of 15 mg of Pd/C, 10% and HClc (2 mL). The mixture was stirred under hydrogen balloon overnight to give 3-(2-methylcarbamoyl-pyridine-5-yl)-propionic acid which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08252793B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-05ab741413ac42dcb890db7e981f456a |
| Source note | uspto-grants-2012_08 |