2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine → HCID 25265087, compound

HRID 889235Notes

Reaction equation

HRID 889235 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[O:20]=[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][N:22]1[C:27]1[O:31][C:30]([C:32](O)=[O:33])=[CH:29][CH:28]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:32]([C:30]1[O:31][C:27]([N:22]2[CH:23]=[CH:24][CH:25]=[CH:26][C:21]2=[O:20])=[CH:28][CH:29]=1)=[O:33]

Participants

3

Procedure

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 5-(2-oxo-2H-pyridin-1-yl)-furan-2-carboxylic acid. MS: 447.2 (M+H).

Sources & evidence

ORD record
ord-078e203995fd4f539eaa35a1b44cb184
Source dataset
uspto-grants-2012_08
Patent number
US08252824B2

Reaction notes

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