Water → HCID 68429698, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of (2-benzyloxy-6-fluorophenyl)-carbamic acid tert-butyl ester (2.35 g, 7.41 mmol) in DMF (20 mL) at 0° C. is added NBS (1.45 g, 8.15 mmol). The mixture is stirred at 0° C. for 30 min., and then at RT for 18 h. It is then poured into water, extracted with EtOAc, washed with water and brine, and dried with MgSO4. The solvent is removed to give the title compound and it is used in the next step.

Provenance & Evidence