HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 68707401, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Isopropyl isocyanate | HCID 61277 | — |
| Reactant | HCID 68704213 | HCID 68704213 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 68707401 | HCID 68707401 | — |
Reaction Steps
40.0 mg (470 μmol) isopropyl isocyanate are dissolved in 5 ml DMF under argon, 80.0 mg (235 μmol) of the compound from Example 35 and 71.4 mg (705 μmol) triethylamine are added and the mixture is stirred overnight at RT. The mixture is then concentrated and the residue is purified by means of preparative HPLC (RP18 column; mobile phase: acetonitrile/water gradient with addition of 0.1% conc. hydrochloric acid).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08252817B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-49bcf54c888c4aeab84a65916c7407ad |
| Source note | uspto-grants-2012_08 |