HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Chlorophenyl)hydrazine → [2-(4-Chloro-phenyl)-2,4,5,6,7,8-hexahydro-cycloheptapyrazol-3-yl]-cyclohexyl-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Chlorophenyl)hydrazine | HCID 70624 | — |
| Reactant | 2-Cyclohexyl-3-oxo-3-(2-oxo-cycloheptyl)-propionic acid ethyl ester | HCID 67387282 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | [2-(4-Chloro-phenyl)-2,4,5,6,7,8-hexahydro-cycloheptapyrazol-3-yl]-cyclohexyl-acetic acid ethyl ester | HCID 67387348 | — |
Reaction Steps
In analogy to the procedure described in example 1.3, 2-cyclohexyl-3-oxo-3-(2-oxo-cycloheptyl)-propionic acid ethyl ester was condensed with (4-chloro-phenyl)-hydrazine (CAS Reg. No. 1073-69-4) in ethanol to give the title compound as orange oil. MS: m/e=415.3 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08252826B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-679dbc9fa00047bf8b77c5298b0ad613 |
| Source note | uspto-grants-2012_08 |