HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxybenzaldehyde → tert-Butyl 3-{[(4-methoxyphenyl)methyl]amino}azetidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxybenzaldehyde | HCID 31244 | — |
| Reactant | Tert-butyl 3-aminoazetidine-1-carboxylate | HCID 1516507 | — |
| Reactant | N-[(4-methoxyphenyl)methyl]cyclobutanamine | HCID 59313984 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | tert-Butyl 3-{[(4-methoxyphenyl)methyl]amino}azetidine-1-carboxylate | HCID 59313975 | — |
Reaction Steps
6A was prepared from 4-methoxybenzaldehyde and tert-butyl 3-aminoazetidine-1-carboxylate following the procedure employed for the preparation of 4A. HPLC: Rt=3.0 min (PHENOMENEX® Luna C18 4.6×30 mm 3 u, 10-90% aqueous methanol containing 0.1% TFA in 2 min; 4 mL/min flow). MS (ES): m/z=293.9 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08252795B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-357860474ca14831b888fe7ee6127f6a |
| Source note | uspto-grants-2012_08 |