Pyridine → 8-Benzyl-1-phenyl-1,8-diaza-spiro[4.5]dec-3-en-2-one

HRID 88977Notes

Reaction equation

HRID 88977 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]2([CH:12]([OH:23])[CH2:13][C:14](=[O:22])[N:15]2[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[CH2:24][CH2:25]1.[S:26]([Cl:27])([Cl:28])=[O:29].[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]2([CH:12]=[CH:13][C:14](=[O:22])[N:15]2[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[CH2:24][CH2:25]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 24386Thionyl ChlorideHCID 127113878-Benzyl-4-hydroxy-1-phenyl-1,8-diazaspiro[4.5]decan-2-one

Product 1

HCID 127113908-Benzyl-1-phenyl-1,8-diaza-spiro[4.5]dec-3-en-2-one

Sources & evidence

ORD record
ord-29096bcbfe764be5ac688e138f5f6eca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…