2-Chloropyridine → HCID 9944975, compound

HRID 889816Notes

Reaction equation

HRID 889816 reaction equation
[O:1]([C:8]1[CH:18]=[CH:17][C:11]([O:12][CH2:13][C@@H:14]([OH:16])[CH3:15])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=1>>[CH3:15][C@H:14]([O:16][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=1)[CH2:13][O:12][C:11]1[CH:17]=[CH:18][C:8]([O:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 79772-ChloropyridineHCID 9834706HCID 9834706, compound

Product 1

HCID 9944975HCID 9944975, compound

Procedure

The resulting (S)-(+)-1-(4-phenoxyphenoxy)-2-propanol was reacted with 2-chloropyridine in the same manner as described in Example 1 to give (S)-(+)-2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine.

Sources & evidence

ORD record
ord-c39e5ef8879248a6b1ce240669471ad7
Source dataset
uspto-grants-2006_02
Patent number
US06995110B2

Reaction notes

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