Ethyl 2-(3-(4-fluorobenzyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylate → 2-(3-(4-Fluorobenzyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylic acid

HRID 89008Notes

Reaction equation

HRID 89008 reaction equation
[CH3:1][c:2]1[cH:3][c:4]([N:5]2[CH2:6][CH2:7][N:8]([CH2:9][c:10]3[cH:11][cH:12][c:13]([C:14]([F:15])([F:16])[F:17])[cH:18][cH:19]3)[C:20]2=[O:21])[s:22][c:23]1[C:24]([O:25][CH2:26][CH3:27])=[O:28].[F:29][c:30]1[cH:31][cH:32][c:33]([CH2:34][N:35]2[C:36](=[O:51])[N:37]([c:40]3[s:41][c:42]([C:46](=[O:47])[O:48][CH2:49][CH3:50])[c:43]([CH3:45])[n:44]3)[CH2:38][CH2:39]2)[cH:52][cH:53]1>>[F:29][c:30]1[cH:31][cH:32][c:33]([CH2:34][N:35]2[C:36](=[O:51])[N:37]([c:40]3[s:41][c:42]([C:46](=[O:47])[OH:48])[c:43]([CH3:45])[n:44]3)[CH2:38][CH2:39]2)[cH:52][cH:53]1

Participants

3

Reactant 2

HCID 57919911Ethyl 2-(3-(4-fluorobenzyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylateHCID 58031427Ethyl 3-methyl-5-(2-oxo-3-(4-(trifluoromethyl)benzyl)imidazolidin-1-yl)thiophene-2-carboxylate

Product 1

HCID 579197992-(3-(4-Fluorobenzyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylic acid

Sources & evidence

ORD record
ord-a42e6c09dfc44a72aab985e2137ac497
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…