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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 890142Generated: October 30, 2026

HCID 11508814, compound → HCID 178487374, compound

https://huagongshe.com/reaction/890142

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 11508814HCID 11508814—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 178487374HCID 178487374114.2%

Reaction Steps

To a solution of the product of Step 2 (114 mg, 0.31 mmol) in 15 mL of MeOH was added 100 mg of 10% Pd/C and the solution was purged with H2. The solution was then stirred under H2 atmosphere overnight. After filtration and concentration, the desired 4-(7-methoxy-2-methyl-quinolin-4-yl)-1H-imidazole-2-ylamine (90 mg, 87%) was obtained as a HBr salt. MS (ESI) (M+1)=255.33. Step 4

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06995181B2
Source datasetuspto-grants-2006_02
ORD IDord-be01bae4456440d8917e9a75e618f0d5
Source noteuspto-grants-2006_02