HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11508814, compound → HCID 178487374, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11508814 | HCID 11508814 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178487374 | HCID 178487374 | 114.2% |
Reaction Steps
To a solution of the product of Step 2 (114 mg, 0.31 mmol) in 15 mL of MeOH was added 100 mg of 10% Pd/C and the solution was purged with H2. The solution was then stirred under H2 atmosphere overnight. After filtration and concentration, the desired 4-(7-methoxy-2-methyl-quinolin-4-yl)-1H-imidazole-2-ylamine (90 mg, 87%) was obtained as a HBr salt. MS (ESI) (M+1)=255.33. Step 4
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06995181B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-be01bae4456440d8917e9a75e618f0d5 |
| Source note | uspto-grants-2006_02 |