Phenoxyethanol → HCID 69590327, compound

Participants

Reaction Steps

250 mg (0.69 mmol) of mono(2-cyanoethyl) 4-(3-chlorophenyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, 0.1 ml (0.8 mmol) of 2-phenyloxyethanol, 187 mg (0.98 mmol) of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride and 18 mg (0.15 mmol) of 4-dimethylaminopyridine were stirred at room temperature for 2 days. Water was added to the obtained mixture. After the extraction with chloroform, the organic layer was dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure, and the residue was purified by the silica gel chromatography (hexane/ethyl acetate=2/1) to obtain the title compound.

Provenance & Evidence