3-Chlorobenzaldehyde → HCID 69590140, compound

Participants

Reaction Conditions

Reaction Steps

465 mg (2.0 mmol) of (3-phenyl-2-propene-1-yl) 3-oxovalerate, 309 mg (2.0 mmol) of (2-cyanoethyl) 3-aminocrotonate and 0.227 ml (2.0 mmol) of 3-chlorobenzaldehyde were heated at 70° C. under stirring in 10 ml of 2-propanol overnight. The reaction mixture was further heated at 120° C. under stirring under atmospheric pressure for 3 hours to evaporate 2-propanol. The residue was purified by the silica gel chromatography (hexane/ethyl acetate=2/1) to obtain the title compound.

Provenance & Evidence