HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2RS,5RS)-2-(2-chloro-ethyl)-5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidine → (2RS,5SR)-2-{2-[5-(4-Fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-ethyl}-2H-tetrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2RS,5RS)-2-(2-chloro-ethyl)-5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidine | HCID 22250484 | — |
| Reactant | HCID 178418441 | HCID 178418441 | — |
| Product | (2RS,5SR)-2-{2-[5-(4-Fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-ethyl}-2H-tetrazole | HCID 22250455 | — |
Reaction Steps
The title compound, colorless oil, MS: m/e=416.2 (M+H+), was prepared in accordance with the general method of example 82b from (2RS,5RS)-2-(2-chloro-ethyl)-5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidine and 1H-tetrazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06995182B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-db9913d914794dac8ed87bc010e5c0a0 |
| Source note | uspto-grants-2006_02 |