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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 890296Generated: October 30, 2026

Methyl iodide → HCID 22250439, compound

https://huagongshe.com/reaction/890296

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium hydrideHCID 24758—
ReactantHCID 22250425HCID 22250425—
ProductHCID 22250439HCID 22250439—

Reaction Steps

The title compound, light yellow oil, MS: m/e=428.5 (M+H+), was prepared by methylation of (2RS,5SR)-2-{2-[5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-ethyl}-1H-imidazole in accordance with the general method of example 8 (methyl iodide, sodium hydride).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06995182B2
Source datasetuspto-grants-2006_02
ORD IDord-860be4faf0b94e3eb50c653771a01a41
Source noteuspto-grants-2006_02