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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 890312Generated: October 31, 2026

(2RS,5RS)-2-(4-chloro-butyl)-5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidine → (2RS,5RS)-2-{4-[5-(4-Fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-butyl}-2H-tetrazole

https://huagongshe.com/reaction/890312

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2RS,5RS)-2-(4-chloro-butyl)-5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidineHCID 22250478—
ReactantHCID 178418441HCID 178418441—
Product(2RS,5RS)-2-{4-[5-(4-Fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-butyl}-2H-tetrazoleHCID 10203835—

Reaction Steps

The title compound, colorless oil, MS: m/e=444.3 (M+H+), was prepared in accordance with the general method of example 82b from (2RS,5RS)-2-(4-chloro-butyl)-5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidine and 1H-tetrazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06995182B2
Source datasetuspto-grants-2006_02
ORD IDord-b70f2ffed20147f98db5b1dba8f4f014
Source noteuspto-grants-2006_02