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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 890316Generated: October 31, 2026

Aluminium lithium hydride → HCID 22250530, compound

https://huagongshe.com/reaction/890316

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAluminium lithium hydrideHCID 21226445—
ReactantHCID 69596798HCID 69596798—
SolventTetrahydrofuranHCID 8028—
ProductHCID 22250530HCID 22250530—

Reaction Steps

Reduction of (2RS,5RS)-5-[5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-pentanoic acid methyl ester with lithium aluminum hydride (1.5 eq.) in THF at RT, aqueous work-up and purification by column chromatography yielded the title compound as a light orange oil, MS: m/e=406.2 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06995182B2
Source datasetuspto-grants-2006_02
ORD IDord-9526159ad1384237a60de8e98b4935a3
Source noteuspto-grants-2006_02