HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 69641953, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 5-Chloromethyl-2-(4-trifluoromethoxy-phenyl)-pyridine | HCID 21935672 | — |
| Reactant | tert-Butyl (6-hydroxy-1H-indol-1-yl)acetate | HCID 69283069 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 69641953 | HCID 69641953 | — |
Reaction Steps
In analogy to the procedure described in example 7 a], (6-hydroxy-indol-1-yl)-acetic acid tert-butyl ester (example 5 b]) was reacted with 5-chloromethyl-2-(4-trifluoromethoxy-phenyl)-pyridine in the presence of cesium carbonate and potassium iodide, using acetonitrile as solvent, to obtain the title compound as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06995263B2 |
| Source dataset | uspto-grants-2006_02 |
| ORD ID | ord-5a2cc3e9241d4ffa9929e2498078bbb2 |
| Source note | uspto-grants-2006_02 |