Thionyl Chloride → HCID 21935643, compound

HRID 890466Notes

Reaction equation

HRID 890466 reaction equation
[F:1][C:2]([F:22])([F:21])[C:3]1[CH:8]=[C:7]([C:9]2[CH:14]=[CH:13][C:12]([C:15]([F:18])([F:17])[F:16])=[CH:11][CH:10]=2)[N:6]=[CH:5][C:4]=1[CH2:19]O.S(Cl)([Cl:25])=O>>[Cl:25][CH2:19][C:4]1[C:3]([C:2]([F:22])([F:21])[F:1])=[CH:8][C:7]([C:9]2[CH:14]=[CH:13][C:12]([C:15]([F:18])([F:17])[F:16])=[CH:11][CH:10]=2)=[N:6][CH:5]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 21935795HCID 21935795, compound

Product 1

HCID 21935643HCID 21935643, compound

Procedure

In analogy to the procedure described in example 1 g], [4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-yl]-methanol was reacted with thionyl chloride to give the title compound as off-white crystals.

Sources & evidence

ORD record
ord-6966d37d69aa46abafc93194436e5c4a
Source dataset
uspto-grants-2006_02
Patent number
US06995263B2

Reaction notes

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