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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 890481Generated: October 29, 2026

Lithium Hydroxide → {6-[2-Methyl-6-(4-trifluoromethoxy-phenyl)-4-trifluoromethyl-pyridin-3-ylmethoxy]-indol-1-yl}-acetic acid

https://huagongshe.com/reaction/890481

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 86597782HCID 86597782—
Product{6-[2-Methyl-6-(4-trifluoromethoxy-phenyl)-4-trifluoromethyl-pyridin-3-ylmethoxy]-indol-1-yl}-acetic acidHCID 11226238—

Reaction Steps

In analogy to the procedure described in example 5 g], {6-[2-methyl-6-(4-trifluoromethoxy-phenyl)-4-trifluoromethyl-pyridin-3-ylmethoxy]-indol-1-yl}-acetic acid ethyl ester was treated with LiOH to obtain the title compound as colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06995263B2
Source datasetuspto-grants-2006_02
ORD IDord-20e57c7176964e43a811b70f23344dc7
Source noteuspto-grants-2006_02