2-Chloroimidazoline sulfate → HCID 178492361, compound

HRID 890620Notes

Reaction equation

HRID 890620 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)=[O:10])=[CH:4][CH:3]=1.S(O)(O)(=O)=O.[Cl:25][C:26]1[NH:27][CH2:28][CH2:29][N:30]=1>>[ClH:25].[NH:27]1[CH2:28][CH2:29][NH:30][C:26]1=[N:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]([NH:11][C:12]2[CH:13]=[CH:14][C:15]([O:18][CH3:19])=[CH:16][CH:17]=2)=[O:10])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 125033982-Chloroimidazoline sulfateHCID 16793124HCID 16793124, compound

Product 1

HCID 178492361HCID 178492361, compoundYield 10%

Procedure

2-(4-Amino-phenyl)-N-(4-methoxy-phenyl)-acetamide (732 mg) was treated with 2-chloroimidazoline sulfate using the procedure of Example 1 above, to yield 2-[4-(Imidazolidin-2-ylideneamino)-phenyl]-N-(4-methoxy-phenyl)-acetamide hydrochloride (10%); Mass Spec M+H: 314.

Sources & evidence

ORD record
ord-03ee367438d445c7a95c883bab072007
Source dataset
uspto-grants-2006_02
Patent number
US06998414B2

Reaction notes

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