Potassium Hydroxide → 2-Acetylheptanoic acid

HRID 890699Notes

Reaction equation

HRID 890699 reaction equation
[C:1]([CH:4]([CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[C:5]([O:7]C)=[O:6])(=[O:3])[CH3:2].[OH-].[K+]>ClCCl>[C:1]([CH:4]([CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[C:5]([OH:7])=[O:6])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 10511765Methyl 2-acetylheptanoate

Product 1

HCID 149151282-Acetylheptanoic acid

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Analogously to Example 15A, 900 mg (5.23 mmol) of methyl 2-acetylheptanoate (Example 16A) are reacted with 2.5 ml of a 3.5 M potassium hydroxide solution to give 2-acetylheptanoic acid in dichloromethane.

Sources & evidence

ORD record
ord-77d184b850094ce09d442932cf526662
Source dataset
uspto-grants-2006_02
Patent number
US06998402B2

Reaction notes

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