Potassium Hydroxide → 2-Acetyloctanoic acid

HRID 890701Notes

Reaction equation

HRID 890701 reaction equation
[C:1]([CH:4]([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[C:5]([O:7]C)=[O:6])(=[O:3])[CH3:2].[OH-].[K+]>ClCCl>[C:1]([CH:4]([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[C:5]([OH:7])=[O:6])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 3390996Methyl 2-acetyloctanoate

Product 1

HCID 187645892-Acetyloctanoic acid

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Analogously to Example 15A, 3.16 g (15.8 mmol) of methyl 2-acetyloctanoate (Example 18A) are reacted with 7 ml of a 3.5 M potassium hydroxide solution to give 2-acetyloctanoic acid in dichloromethane.

Sources & evidence

ORD record
ord-886cf3830eeb4a458a9a334853f91937
Source dataset
uspto-grants-2006_02
Patent number
US06998402B2

Reaction notes

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