Ammonium → Diethyl 2-(6-methoxypyridin-2-yl)malonate

HRID 89080Notes

Reaction equation

HRID 89080 reaction equation
[Br:1][c:2]1[n:3][c:4]([O:8][CH3:9])[cH:5][cH:6][cH:7]1.[C:19](=[O:20])([O-:21])[O-:22].[C:25]([CH2:26][C:27](=[O:28])[O:29][CH2:30][CH3:31])(=[O:32])[O:33][CH2:34][CH3:35].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[Cl-:36].[Cs+:23].[Cs+:24].[Cu:44][I:45].[NH4+:37].[O:38]1[CH2:39][CH2:40][O:41][CH2:42][CH2:43]1.[c:10]1([C:11]([OH:12])=[O:13])[n:14][cH:15][cH:16][cH:17][cH:18]1>>[c:2]1([CH:26]([C:25](=[O:32])[O:33][CH2:34][CH3:35])[C:27](=[O:28])[O:29][CH2:30][CH3:31])[n:3][c:4]([O:8][CH3:9])[cH:5][cH:6][cH:7]1

Participants

11

Reactant 10

HCID 223AmmoniumHCID 312ChlorideHCID 1018Picolinic acidHCID 7761Diethyl MalonateHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 2568102-Bromo-6-methoxypyridine

Product 1

HCID 59636709Diethyl 2-(6-methoxypyridin-2-yl)malonate

Sources & evidence

ORD record
ord-34725a4d3e7c42e5b591d279de20c968
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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