3-(2-Methoxyethyl)-2,3,4,5-tetrahydro-1h-3-benzazepin-7-amine → 2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]-pyrimidin-4-ylamino}-5-dimethylamino-N,N-dimethyl-benzenesulfonamide

HRID 89084Notes

Reaction equation

HRID 89084 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:12][c:13]([NH2:16])[cH:14][cH:15]2)[CH2:10][CH2:11]1.[Cl:17][c:18]1[n:19][cH:20][c:21]([Cl:40])[c:22]([NH:24][c:25]2[c:26]([S:34](=[O:35])(=[O:36])[N:37]([CH3:38])[CH3:39])[cH:27][c:28]([N:31]([CH3:32])[CH3:33])[cH:29][cH:30]2)[n:23]1>>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:12][c:13]([NH:16][c:18]3[n:19][cH:20][c:21]([Cl:40])[c:22]([NH:24][c:25]4[c:26]([S:34](=[O:35])(=[O:36])[N:37]([CH3:38])[CH3:39])[cH:27][c:28]([N:31]([CH3:32])[CH3:33])[cH:29][cH:30]4)[n:23]3)[cH:14][cH:15]2)[CH2:10][CH2:11]1

Participants

3

Reactant 2

HCID 574160893-(2-Methoxyethyl)-2,3,4,5-tetrahydro-1h-3-benzazepin-7-amineHCID 866339412-(2,5-Dichloro-pyrimidin-4-ylamino)-5-dimethylamino-N,N-dimethyl-benzenesulfonamide

Product 1

HCID 668303322-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]-pyrimidin-4-ylamino}-5-dimethylamino-N,N-dimethyl-benzenesulfonamide

Sources & evidence

ORD record
ord-268d070ec3764ff1b775d08ff22d70f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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